FLNC Antibody

Product Specifications

Background

This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

2318

Swiss Prot

Q14315

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 2160-2340 of human FLNC (NP_001449.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 302kDa

Fragment

IgG

Symbol

FLNC

Positive Control 2

LO2

Positive Control 3

NIH/3T3

NCBI Official Name

Filamin C

NCBI Organism

Homo sapiens

Other Product Names

ABP-28ABP280A, ABPA, ABPL, CMH26, FLN2, MFM5, MPD4, RCM5, filamin-C, ABP-280-like protein, ABP-L, gamma filamin, actin binding protein 28filamin C, gamma, filamin-2, gamma filamin