CEL Antibody

Product Specifications

Background

The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.

NCBI Gene ID

1056

Swiss Prot

P19835

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 350-550 of human CEL (NP_001798.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

Affinity purification

Positive Control

Mouse pancreas

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 67kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CEL

NCBI Official Name

Carboxyl ester lipase

NCBI Organism

Homo sapiens

Other Product Names

BAL, BSDL, BSSLL, CEase, FAP, FAPP, LIPA, MODY8, CEL, bile salt-activated lipase, bile salt-dependent lipase, oncofetal isoform, bucelipase, carboxyl ester hydrolase, carboxyl ester lipase (bile salt-stimulated lipase), cholesterol esterase, fetoacinar pancreatic protein, lysophospholipase, pancreatic, sterol esterase