P2RX3 Antibody
Product Specifications
Background
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
NCBI Gene ID
5024
Swiss Prot
P56373
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 328-397 of human P2RX3 (NP_002550.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 44kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:1000
Symbol
P2RX3
Positive Control 2
Mouse heart
Positive Control 3
Rat liver
NCBI Official Name
P2X purinoceptor 3
NCBI Organism
Homo sapiens
Other Product Names
P2X purinoceptor 3, P2X3, ATP receptor, Purinergic receptor, P2RX3
Tested Applications
WB
Physical Properties
Liquid
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