AASS Antibody
Product Specifications
Background
This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
NCBI Gene ID
10157
Swiss Prot
Q9UDR5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 180-400 of human AASS (NP_005754.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 102kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
AASS
Positive Control 2
Mouse kidney
Positive Control 3
Mouse liver
Positive Control 4
Mouse heart
Positive Control 5
Mouse brain
Positive Control 6
Rat kidney
NCBI Official Name
Alpha-aminoadipic semialdehyde synthase, mitochondrial
NCBI Organism
Homo sapiens
Other Product Names
Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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