SLC10A2 Antibody

Product Specifications

Background

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM) ; muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG) .

NCBI Gene ID

6555

Swiss Prot

Q12908

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 289-348 of human SLC10A2 (NP_000443.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

HT-29

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 38kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SLC10A2

Positive Control 2

Mouse small intestine

Positive Control 3

Mouse kidney

Positive Control 4

Rat small intestine

Positive Control 5

Rat liver

NCBI Official Name

Solute carrier family 10 (sodium/bile acid cotransporter), member 2

NCBI Organism

Homo sapiens

Other Product Names

Ileal sodium-dependent bile acid transporter, ileal apical sodium-dependent bile acid transporter, OTTHUMP00000040691, NTCP2, ISBT, solute carrier family 10 (sodium/bile acid cotransporter family), member 2, ASBT, SLC10A2