CDK11B Antibody

Product Specifications

Background

This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

984

Swiss Prot

P21127

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human CDK11B (NP_277021.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 110kDa

Fragment

IgG

Symbol

CDK11B

Positive Control 2

Mouse brain

NCBI Official Name

Cyclin dependent kinase 11B

NCBI Organism

Homo sapiens

Other Product Names

CDC2L1, CDK11, CDK11-p11CDK11-p46, CDK11-p58, CLK-1, PITSLREA, PK58, p58, p58CDC2L1, p58CLK-1, cyclin-dependent kinase 11B, CDC-related protein kinase p58, PITSLRE serine/threonine-protein kinase CDC2L1, cell division cycle 2-like 1 (PITSLRE proteins), cell division protein kinase 11B, galactosyltransferase-associated protein kinase p58/GTA, p58 CLK-1