ITPR3 Antibody
Product Specifications
Background
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
NCBI Gene ID
3710
Swiss Prot
Q14573
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1630-1870 of human ITPR3 (NP_002215.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 300kDa
Fragment
IgG
Symbol
ITPR3
Positive Control 2
LO2
Positive Control 3
HepG2
NCBI Official Name
Inositol 1,4,5-trisphosphate receptor, type 3
NCBI Organism
Homo sapiens
Other Product Names
ITPR3, inositol 1, 4, 5-triphosphate receptor, type 3, HGNC:6182, FLJ36205, IP3R, IP3R3
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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