MTHFS Antibody
Product Specifications
Background
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.
NCBI Gene ID
10588
Swiss Prot
P49914
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-203 of human MTHFS (NP_006432.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 23kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MTHFS
Positive Control 2
A-549
Positive Control 3
HepG2
Positive Control 4
HeLa
Positive Control 5
Jurkat
Positive Control 6
Mouse liver
NCBI Official Name
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NCBI Organism
Homo sapiens
Other Product Names
MTHFS, FLJ30410, HsT19268
Tested Applications
WB
Physical Properties
Liquid
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