NAT2 Antibody
Product Specifications
Background
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2) .
NCBI Gene ID
10
Swiss Prot
P11245
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 171-290 of human NAT2 (NP_000006.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 36kDa
Fragment
IgG
Symbol
NAT2
Positive Control 2
Mouse heart
Positive Control 3
Mouse liver
Positive Control 4
Mouse kidney
NCBI Official Name
N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCBI Organism
Homo sapiens
Other Product Names
NAT2, AAC2, PNAT, NAT-2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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