MOGS Antibody
Product Specifications
Background
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb) . Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
7841
Swiss Prot
Q13724
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human MOGS (NP_006293.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 80kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MOGS
Positive Control 2
LO2
Positive Control 3
BxPC-3
Positive Control 4
OVCAR-3
Positive Control 5
Mouse Brain
Positive Control 6
Mouse Liver
NCBI Official Name
Mannosyl-oligosaccharide glucosidase
NCBI Organism
Homo sapiens
Other Product Names
GCS1, DER7, GCS1, CDG2B, CWH41
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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