SDC2 Antibody

Product Specifications

Background

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.

NCBI Gene ID

6383

Swiss Prot

P34741

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 19-144 of human SDC2 (NP_002989.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Growth Factors, Immunology, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 37kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

SDC2

Positive Control 2

U-251MG

Positive Control 3

HepG2

Positive Control 4

HeLa

NCBI Official Name

Syndecan 2

NCBI Organism

Homo sapiens

Other Product Names

CD362, HSPG, HSPG1, SYND2, syndecan-2, cell surface-associated heparan sulfate proteoglycan 1, fibroglycan, heparan sulfate proteoglycan 1, cell surface-associated, heparan sulfate proteoglycan core protein, syndecan proteoglycan 2