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PRMT7 Antibody

Product Specifications

Background

This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients.

NCBI Gene ID

54496

Swiss Prot

Q9NVM4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 513-692 of human PRMT7 (NP_061896.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 75kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PRMT7

Positive Control 2

HeLa

Positive Control 3

MCF7

Positive Control 4

Mouse testis

Positive Control 5

Rat testis

NCBI Official Name

Protein arginine methyltransferase 7

NCBI Organism

Homo sapiens

Other Product Names

[Myelin basic protein]-arginine N-methyltransferase PRMT7, FLJ10640, histone-arginine N-methyltransferase PRMT7, KIAA1933, myelin basic protein-arginine N-methyltransferase, OTTHUMP00000174863, PRMT7, protein arginine methyltransferase 7, protein arginine N-methyltransferase 7

Tested Applications

WB

Physical Properties

Liquid

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