SHMT2 Antibody
Product Specifications
Background
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
6472
Swiss Prot
P34897
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 265-504 of human SHMT2 (NP_005403.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 52kDa
Fragment
IgG
Symbol
SHMT2
Positive Control 2
OVCAR3
Positive Control 3
22Rv1
Positive Control 4
Mouse liver
Positive Control 5
Mouse kidney
NCBI Official Name
Serine hydroxymethyltransferase 2 (mitochondrial)
NCBI Organism
Homo sapiens
Other Product Names
SHMT2, GLYA, SHMT, HEL-S-51e
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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