STAT1 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
NCBI Gene ID
6772
Swiss Prot
P42224
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 650-750 of human STAT1 (NP_009330.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction, Transcription, Inflammasomes
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 91kDa
Fragment
IgG
Symbol
STAT1
NCBI Official Name
Signal transducer and activator of transcription 1, 91kDa
NCBI Organism
Homo sapiens
Other Product Names
STAT1 alpha Antibody: CANDF7, ISGF-3, STAT91
Tested Applications
WB, IHC, IF, IP
Physical Properties
Liquid
Curated Selection
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