CHD4 Antibody
Product Specifications
Background
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
1108
Swiss Prot
Q14839
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1520-1690 of human CHD4 (NP_001264.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 280kDa
Fragment
IgG
Symbol
CHD4
Positive Control 2
Jurkat
Positive Control 3
293T
Positive Control 4
HT-1080
NCBI Official Name
Chromodomain helicase DNA binding protein 4
NCBI Organism
Homo sapiens
Other Product Names
CHD4, ATP-dependent helicase CHD4, CHD-4, Mi-2b, Mi2-BETA
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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