YAP1 Antibody

Product Specifications

Background

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

NCBI Gene ID

10413

Swiss Prot

P46937

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 75kDa

Fragment

IgG

Symbol

YAP1

Positive Control 2

HeLa

Positive Control 3

BT-474

Positive Control 4

Mouse liver

NCBI Official Name

Yes-associated protein 1

NCBI Organism

Homo sapiens

Other Product Names

YAP1, YAP, YAP2, YAP65, YKI

Tested Applications

WB, IF

Physical Properties

Liquid

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