C5AR2 Antibody
Product Specifications
Background
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
27202
Swiss Prot
Q9P296
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 258-337 of human C5AR2 (NP_060955.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
LO2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 36kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
C5AR2
Positive Control 2
293T
Positive Control 3
Mouse liver
NCBI Official Name
Complement component 5a receptor 2
NCBI Organism
Homo sapiens
Other Product Names
GPR77, G-protein coupled receptor 77, GPF77, C5L2, G protein-coupled receptor 77
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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