PRLR Antibody
Product Specifications
Background
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
NCBI Gene ID
5618
Swiss Prot
P16471
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 25-234 of human PRLR (NP_000940.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 70kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
PRLR
Positive Control 2
MCF7
Positive Control 3
Mouse ovary
NCBI Official Name
Prolactin receptor
NCBI Organism
Homo sapiens
Other Product Names
PRLR, HPRL receptor, PRL-R, HPRLrI, Prolactin receptor
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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