CHFR Antibody
Product Specifications
Background
This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described.
NCBI Gene ID
55743
Swiss Prot
Q96EP1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human CHFR (NP_001154818.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Affinity purification
Positive Control
HT-1080
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 70kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CHFR
Positive Control 2
22Rv1
Positive Control 3
HepG2
Positive Control 4
Mouse kidney
Positive Control 5
Mouse testis
NCBI Official Name
Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
NCBI Organism
Homo sapiens
Other Product Names
CHFR, FLJ10796, FLJ33629, RNF116, RNF196
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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