YWHAB Antibody

Product Specifications

Background

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.

NCBI Gene ID

7529

Swiss Prot

P31946

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human YWHAB (NP_647539.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

Mouse intestine

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 28kDa

Fragment

IgG

Symbol

YWHAB

Positive Control 2

Mouse liver

Positive Control 3

Mouse kidney

Positive Control 4

HT-29

Positive Control 5

SW480

Positive Control 6

BT-474

NCBI Official Name

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

NCBI Organism

Homo sapiens

Other Product Names

YWHAB, 14-3-3 alpha, 14-3-3 Beta, 14-3-3 protein beta/alpha, GW128, Protein 1054, HS1, KCIP-1, YWHAA

Tested Applications

WB, IHC

Physical Properties

Liquid

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