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KRT18 Antibody

Product Specifications

Background

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

3875

Swiss Prot

P05783

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 127-430 of human KRT18 (NP_000215.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

K-562

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 48kDa

Fragment

IgG

Symbol

KRT18

Positive Control 2

HT-29

Positive Control 3

HepG2

Positive Control 4

HeLa

Positive Control 5

Mouse pancreas

NCBI Official Name

Keratin 18

NCBI Organism

Homo sapiens

Other Product Names

KRT18, K18, CYK18

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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