SSB Antibody
Product Specifications
Background
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly (U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
NCBI Gene ID
6741
Swiss Prot
P05455
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 166-408 of human SSB (NP_003133.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 47kDa
Fragment
IgG
Symbol
SSB
Positive Control 2
LO2
Positive Control 3
HepG2
Positive Control 4
293T
NCBI Official Name
Sjogren syndrome antigen B (autoantigen La)
NCBI Organism
Homo sapiens
Other Product Names
SSB, LARP3, La, La/SSB
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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