PHB Antibody
Product Specifications
Background
This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
5245
Swiss Prot
P35232
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 73-272 of human PHB (NP_002625.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 30kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PHB
Positive Control 2
NIH/3T3
Positive Control 3
HeLa
Positive Control 4
MCF7
Positive Control 5
HepG2
Positive Control 6
Mouse liver
NCBI Official Name
Prohibitin
NCBI Organism
Homo sapiens
Other Product Names
PHB, PHB1, HEL-215, HEL-S-54e
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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