CD9 Antibody

Product Specifications

Background

CD9 Antibody: CD9 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Like other tetraspanins, CD9 is a cell surface glycoproteins play a role in many cellular processes including differentiation, adhesion, and signal transduction (1) . CD9 expression plays a critical role in the suppression of cancer cell motility and metastasis. In one study, the knockdown of CD9 expression suppressed the metastatic capacity of human breast cancer cells (2), while other results have shown the opposite effect, suggesting that different proteins associated with CD9 account for its abilities to promote or suppress metastasis (3) .

NCBI Gene ID

928

Swiss Prot

P21926

Accession Number

NP_001760

Host

Rabbit

Reactivity

Human

Immunogen

CD9 antibody was raised against a peptide corresponding to 19 amino acids near the center of human CD9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

CD9 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1384 - Human Uterus Tissue Lysate

Concentration

1 mg/mL

Homology

Predicted species reactivity based on immunogen sequence: Cat: (90%), Bovine: (89%), Mouse: (84%), Rat: (84%), Boar: (78%)

Buffer

CD9 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CD9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Symbol

CD9

NCBI Official Name

CD9

NCBI Organism

Homo sapiens

Background Reference 01

Murayama Y, Oritani K, and Tsutsui S. Novel CD9-targeted therapies in gastric cancer. World J. Gastroenterol. 2015; 21:3206-13.

Background Reference 02

Rappa G, Green TM, Karbanova J, Corbeil D, et al. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget 2015; 6:7970-91.