LANCL2 Antibody

Product Specifications

Background

LANCL2 (LanC-like protein 2), also known as TASP (testis-specific adriamycin sensitivity protein) or GPR69B, is a 450 amino acid member of the LanC-like protein family (1) . It is expressed highly in brain and testis and localized to the nucleus, cytoplasm and cell membrane (2,3) . LANCL2 is necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes (3,4) .

NCBI Gene ID

55915

Swiss Prot

Q9NS86

Accession Number

NP_061167

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

LANCL2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1303 - Human Brain Tissue Lysate

Concentration

1 mg/mL

Buffer

LANCL2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

LANCL2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

LANCL2 antibody is human, mouse and rat reactive.

Symbol

LANCL2

NCBI Official Name

LanC lantibiotic synthetase component C-like 2 (bacterial)

NCBI Organism

Homo sapiens

Background Reference 01

Mayer H, Pongratz M, and Prohaska R. Molecular cloning, characterization, and tissue-specific expression of human LANCL2, a novel member of the LanC-like protein family. DNA Seq. 2001; 12:161-6.

Background Reference 02

Sturla L, Fresia C, Guida L, et al. Binding of abscisic acid to human LANCL2. Biochem. Biophys. Res. Commun. 2011; 415:390-5.

Background Reference 03

Landlinger C, Salzer U, and Prohaska R. Myristoylation of human LanC-like protein 2 (LANCL2) is essential for the interaction with the plasma membrane and the increase in cellular sensitivity to adriamycin. Biochim. Biophys. Acta. 2006; 1758:1759-67.