DAF Antibody

Product Specifications

Background

The decay-accelerating factor (DAF), also known as CD55, is an integral membrane glycoprotein that is involved in the regulation of the complement cascade (1) . DAF limits excessive complement activation by accelerating their decay following DAF binding, thereby disrupting the cascade and preventing damage to host cells (2) . Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) (3) .

NCBI Gene ID

1604

Swiss Prot

P08174

Accession Number

NP_001108224

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

DAF antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1203 - A549 Cell Lysate

Concentration

1 mg/mL

Buffer

DAF antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

DAF antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Fragment

IgG

Specificity

DAF antibody is human specific. At least two isoforms of DAF are known to exist; this antibody will only detect the longest isoform.

Symbol

CD55

Positive Control 2

Cat. No. 10-101 - Human Lung Tissue Slide

Positive Control 3

Cat. No. 1201 – HeLa Cell Lysate

NCBI Official Name

CD55 molecule, decay accelerating factor for complement (Cromer blood group)

NCBI Organism

Homo sapiens

Background Reference 01

Nicholson-Weller A, March JP, Rosen CE, et al. Surface membrane expression by human blood leukocytes and platelts of decay-accelerating factor, a regulatory protein of the complement system. Blood 1985; 65:1237-44.