ABHD6 (NM_020676) Human Recombinant Protein

Product Specifications

Background

Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (PubMed:22969151) . Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways (By similarity) . Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity) . Also able to degrade bis (monoacylglycero) phosphate (BMP) and constitutes the major enzyme for BMP catabolism (PubMed:26491015) . BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting (PubMed:26491015) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human abhydrolase domain containing 6 (ABHD6)

Synonyms

Abhydrolase domain containing 6; lipase protein

Gene ID

57406

UniProt

Q9BV23, A0A024R323

Accession Number mRNA

NM_020676

Chromosomal Location

3p14.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

38.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.