ABHD6 (NM_020676) Human Recombinant Protein
Product Specifications
Background
Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (PubMed:22969151) . Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways (By similarity) . Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity) . Also able to degrade bis (monoacylglycero) phosphate (BMP) and constitutes the major enzyme for BMP catabolism (PubMed:26491015) . BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting (PubMed:26491015) .[UniProtKB/Swiss-Prot Function]
Synonyms
Abhydrolase domain containing 6; lipase protein
Gene ID
57406
UniProt
Q9BV23, A0A024R323
Accession Number mRNA
NM_020676
Chromosomal Location
3p14.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
38.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ABHD6
Species
Human
Protein ID
NP_065727
Overview
Recombinant protein of human abhydrolase domain containing 6 (ABHD6)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57406
Uniprot URL
https://www.uniprot.org/uniprot/Q9BV23
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020676
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_065727
Curated Selection
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