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ORC4L (ORC4) (NM_002552) Human Recombinant Protein

Product Specifications

Background

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene. [provided by RefSeq, Oct 2010]

Synonyms

ORC4L; ORC4P

Gene ID

5000

UniProt

O43929, A8K7H4

Accession Number mRNA

NM_002552

Chromosomal Location

2q23.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cell cycle

Field of Research

Cell cycle

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

50.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ORC4

Species

Human

Protein ID

NP_002543

Overview

Recombinant protein of human origin recognition complex, subunit 4-like (yeast) (ORC4L), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5000

Uniprot URL

https://www.uniprot.org/uniprot/O43929

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002552

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002543

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