ORC4L (ORC4) (NM_002552) Human Recombinant Protein
Product Specifications
Background
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene. [provided by RefSeq, Oct 2010]
Synonyms
ORC4L; ORC4P
Gene ID
5000
UniProt
O43929, A8K7H4
Accession Number mRNA
NM_002552
Chromosomal Location
2q23.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell cycle
Field of Research
Cell cycle
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
50.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ORC4
Species
Human
Protein ID
NP_002543
Overview
Recombinant protein of human origin recognition complex, subunit 4-like (yeast) (ORC4L), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5000
Uniprot URL
https://www.uniprot.org/uniprot/O43929
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002552
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002543
Curated Selection
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