PGD (NM_002631) Human Recombinant Protein
Product Specifications
Background
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Synonyms
6PGD
Gene ID
5226
UniProt
P52209
Accession Number mRNA
NM_002631
Chromosomal Location
1p36.22
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Glutathione metabolism, Metabolic pathways, Pentose phosphate pathway
Field of Research
Glutathione metabolism, Metabolic pathways, Pentose phosphate pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
53 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PGD
Species
Human
Protein ID
NP_002622
Overview
Recombinant protein of human phosphogluconate dehydrogenase (PGD)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5226
Uniprot URL
https://www.uniprot.org/uniprot/P52209
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002631
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002622
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