ACAT2 (NM_005891) Human Recombinant Protein
Product Specifications
Background
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
Synonyms
Acetoacetyl Coenzyme A thiolase; acetyl-Coenzyme A acetyltransferase 2; cytosolic acetoacetyl-CoA thiolase; OTTHUMP00000017527
Gene ID
39
UniProt
Q9BWD1
Accession Number mRNA
NM_005891
Chromosomal Location
6q25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Butanoate metabolism, Fatty acid metabolism, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Tryptophan metabolism, Valine, leucine and isoleucine degradation
Field of Research
Butanoate metabolism, Fatty acid metabolism, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Tryptophan metabolism, Valine, leucine and isoleucine degradation
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
41.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ACAT2
Species
Human
Protein ID
NP_005882
Overview
Recombinant protein of human acetyl-Coenzyme A acetyltransferase 2 (ACAT2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/39
Uniprot URL
https://www.uniprot.org/uniprot/Q9BWD1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005891
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005882
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