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ACAT2 (NM_005891) Human Recombinant Protein

Product Specifications

Background

The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

Overview

Recombinant protein of human acetyl-Coenzyme A acetyltransferase 2 (ACAT2)

Synonyms

Acetoacetyl Coenzyme A thiolase; acetyl-Coenzyme A acetyltransferase 2; cytosolic acetoacetyl-CoA thiolase; OTTHUMP00000017527

Gene ID

39

UniProt

Q9BWD1

Accession Number mRNA

NM_005891

Chromosomal Location

6q25.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Butanoate metabolism, Fatty acid metabolism, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Tryptophan metabolism, Valine, leucine and isoleucine degradation

Field of Research

Butanoate metabolism, Fatty acid metabolism, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Tryptophan metabolism, Valine, leucine and isoleucine degradation

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

41.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ACAT2

Species

Human

Protein ID

NP_005882

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/39

Uniprot URL

https://www.uniprot.org/uniprot/Q9BWD1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005891

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005882

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