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NEUROD1 (NM_002500) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]

Synonyms

BETA2; BHF-1; bHLHa3; MODY6; NEUROD; T2D

Gene ID

4760

UniProt

Q13562

Accession Number mRNA

NM_002500

Chromosomal Location

2q31.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Maturity onset diabetes of the young

Field of Research

Maturity onset diabetes of the young

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors

Molecular Weight

39.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NEUROD1

Species

Human

Protein ID

NP_002491

Overview

Recombinant protein of human neurogenic differentiation 1 (NEUROD1)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4760

Uniprot URL

https://www.uniprot.org/uniprot/Q13562

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002500

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002491

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