BMX (NM_203281) Human Recombinant Protein
Product Specifications
Background
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Synonyms
ETK; PSCTK2; PSCTK3
Gene ID
660
UniProt
P51813
Accession Number mRNA
NM_203281
Chromosomal Location
Xp22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
77.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BMX
Species
Human
Protein ID
NP_975010
Overview
Recombinant protein of human BMX non-receptor tyrosine kinase (BMX), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/660
Uniprot URL
https://www.uniprot.org/uniprot/P51813
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_203281
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_975010
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