Beta Synuclein (SNCB) (NM_003085) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Synonyms
Beta-synuclein; synuclein, beta
Gene ID
6620
UniProt
Q16143
Accession Number mRNA
NM_003085
Chromosomal Location
5q35.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
14.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SNCB
Species
Human
Protein ID
NP_003076
Overview
Recombinant protein of human synuclein, beta (SNCB), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6620
Uniprot URL
https://www.uniprot.org/uniprot/Q16143
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003085
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003076
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