PI3 (NM_002638) Human Recombinant Protein
Product Specifications
Background
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014]
Synonyms
Cementoin; ESI; SKALP; WAP3; WFDC14
Gene ID
5266
UniProt
P19957
Accession Number mRNA
NM_002638
Chromosomal Location
20q13.12
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein, Transmembrane
Molecular Weight
9.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PI3
Species
Human
Protein ID
NP_002629
Overview
Recombinant protein of human peptidase inhibitor 3, skin-derived (PI3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5266
Uniprot URL
https://www.uniprot.org/uniprot/P19957
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002638
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002629
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