BRMS1 (NM_015399) Human Recombinant Protein
Product Specifications
Background
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC) . The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
DKFZp564A063
Gene ID
25855
UniProt
Q9HCU9
Accession Number mRNA
NM_015399
Chromosomal Location
11q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
28.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BRMS1
Species
Human
Protein ID
NP_056214
Overview
Recombinant protein of human breast cancer metastasis suppressor 1 (BRMS1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25855
Uniprot URL
https://www.uniprot.org/uniprot/Q9HCU9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015399
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056214
Curated Selection
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