PHPT1 (NM_014172) Human Recombinant Protein

Product Specifications

Background

This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Overview

Recombinant protein of human phosphohistidine phosphatase 1 (PHPT1), transcript variant 3

Synonyms

CGI-202; HEL-S-132P; HSPC141; PHP; PHP14

Gene ID

29085

UniProt

Q9NRX4, V9HWC4

Accession Number mRNA

NM_014172

Chromosomal Location

9q34.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism

Field of Research

Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

13.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.