DCUN1D3 (NM_173475) Human Recombinant Protein
Product Specifications
Background
Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane (PubMed:25349211) . When overexpressed in transformed cells, may promote mesenchymal to epithelial-like changes and inhibit colony formation in soft agar (PubMed:25349211) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae) (DCUN1D3)
Synonyms
44M2.4; SCCRO3
Gene ID
123879
UniProt
Q8IWE4
Accession Number mRNA
NM_173475
Chromosomal Location
16p12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
34.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DCUN1D3
Species
Human
Protein ID
NP_775746
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/123879
Uniprot URL
https://www.uniprot.org/uniprot/Q8IWE4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_173475
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_775746
Curated Selection
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