USP3 (NM_006537) Human Recombinant Protein
Product Specifications
Background
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.[UniProtKB/Swiss-Prot Function]
Synonyms
SIH003; UBP
Gene ID
9960
UniProt
Q9Y6I4
Accession Number mRNA
NM_006537
Chromosomal Location
15q22.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease
Molecular Weight
58.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
USP3
Species
Human
Protein ID
NP_006528
Overview
Recombinant protein of human ubiquitin specific peptidase 3 (USP3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9960
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y6I4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006537
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006528
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