AGXT (NM_000030) Human Recombinant Protein

Product Specifications

Background

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human alanine-glyoxylate aminotransferase (AGXT)

Synonyms

AGT; AGT1; AGXT1; PH1; SPAT; SPT; TLH6

Gene ID

189

UniProt

P21549

Accession Number mRNA

NM_000030

Chromosomal Location

2q37.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Alanine, aspartate and glutamate metabolism, Glycine, serine and threonine metabolism, Metabolic pathways

Field of Research

Alanine, aspartate and glutamate metabolism, Glycine, serine and threonine metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

42.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.