UBA6 (NM_018227) Human Recombinant Protein
Product Specifications
Background
Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3) . UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]) .[supplied by OMIM, Mar 2008]
Overview
Recombinant protein of human ubiquitin-like modifier activating enzyme 6 (UBA6)
Synonyms
E1-L2; MOP-4; UBE1L2
Gene ID
55236
UniProt
A0AVT1, A1LT96
Accession Number mRNA
NM_018227
Chromosomal Location
4q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
117.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UBA6
Species
Human
Protein ID
NP_060697
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55236
Uniprot URL
https://www.uniprot.org/uniprot/A0AVT1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018227
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060697
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