ELMO1 (NM_001039459) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Overview

Recombinant protein of human engulfment and cell motility 1 (ELMO1), transcript variant 3

Synonyms

CED-12; CED12; ELMO-1

Gene ID

9844

UniProt

Q92556

Accession Number mRNA

NM_001039459

Chromosomal Location

7p14.2-p14.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Chemokine signaling pathway

Field of Research

Chemokine signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

28.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.