ELMO1 (NM_001039459) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Synonyms
CED-12; CED12; ELMO-1
Gene ID
9844
UniProt
Q92556
Accession Number mRNA
NM_001039459
Chromosomal Location
7p14.2-p14.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Chemokine signaling pathway
Field of Research
Chemokine signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
28.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ELMO1
Species
Human
Protein ID
NP_001034548
Overview
Recombinant protein of human engulfment and cell motility 1 (ELMO1), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9844
Uniprot URL
https://www.uniprot.org/uniprot/Q92556
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001039459
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001034548
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