BTN3A1 (NM_007048) Human Recombinant Protein
Product Specifications
Background
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC) -associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]) .[supplied by OMIM, Nov 2010]
Synonyms
BT3.1; BTF5; BTN3.1; CD277
Gene ID
+011118-12-31T23:00:00.000Z
UniProt
O00481
Accession Number mRNA
NM_007048
Chromosomal Location
6p22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
57.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BTN3A1
Species
Human
Protein ID
NP_008979
Overview
Recombinant protein of human butyrophilin, subfamily 3, member A1 (BTN3A1), transcript variant 1
Gene ID URL
+011118-12-31T23:00:00.000Z
Uniprot URL
https://www.uniprot.org/uniprot/O00481
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007048
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_008979
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