MR1 (NM_001531) Human Recombinant Protein
Product Specifications
Background
MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome. [provided by RefSeq, Jul 2015]
Synonyms
HLALS
Gene ID
3140
UniProt
Q95460
Accession Number mRNA
NM_001531
Chromosomal Location
1q25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
39.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MR1
Species
Human
Protein ID
NP_001522
Overview
Recombinant protein of human major histocompatibility complex, class I-related (MR1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3140
Uniprot URL
https://www.uniprot.org/uniprot/Q95460
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001531
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001522
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