SPRR2E (NM_001024209) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a family of small proline-rich proteins clustered in the epidermal differentiation complex on chromosome 1q21. The encoded protein, along with other family members, is a component of the cornified cell envelope that forms beneath the plasma membrane in terminally differentiated stratified squamous epithelia. This envelope serves as a barrier against extracellular and environmental factors. The seven SPRR2 genes (A-G) appear to have been homogenized by gene conversion compared to others in the cluster that exhibit greater differences in protein structure. [provided by RefSeq, Feb 2014]
Gene ID
6704
UniProt
P22531
Accession Number mRNA
NM_001024209
Chromosomal Location
1q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
7.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SPRR2E
Species
Human
Protein ID
NP_001019380
Overview
Recombinant protein of human small proline-rich protein 2E (SPRR2E)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6704
Uniprot URL
https://www.uniprot.org/uniprot/P22531
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001024209
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001019380
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