CHMP4A (NM_014169) Human Recombinant Protein
Product Specifications
Background
CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs) . Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]) .[supplied by OMIM, Mar 2008]
Synonyms
C14orf123; CHMP4; CHMP4B; HSPC134; SHAX2; SNF7; SNF7-1; VPS32-1; VPS32A
Gene ID
29082
UniProt
Q9BY43, Q14D22
Accession Number mRNA
NM_014169
Chromosomal Location
14q12
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis
Field of Research
Endocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
29.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CHMP4A
Species
Human
Protein ID
NP_054888
Overview
Recombinant protein of human chromatin modifying protein 4A (CHMP4A)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/29082
Uniprot URL
https://www.uniprot.org/uniprot/Q9BY43
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014169
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_054888
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