DOK3 (NM_024872) Human Recombinant Protein
Product Specifications
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Homo sapiens docking protein 3 (DOK3), transcript variant 1
Synonyms
DOKL
Gene ID
79930
UniProt
Q7L591, A0A024R7M5
Accession Number mRNA
NM_024872
Chromosomal Location
5q35.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
53.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DOK3
Species
Human
Protein ID
NP_079148
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79930
Uniprot URL
https://www.uniprot.org/uniprot/Q7L591
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024872
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079148
Curated Selection
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