Gadd45a (NM_007836) Mouse Recombinant Protein

Product Specifications

Background

Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AA545191; Ddit1; GADD45

Gene ID

13197

UniProt

P48316, Q3UMH6

Accession Number mRNA

NM_007836

Chromosomal Location

6 C1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

18.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Gadd45a

Species

Mouse

Protein ID

NP_031862

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/13197

Uniprot URL

https://www.uniprot.org/uniprot/P48316

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_007836

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_031862

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