Gadd45a (NM_007836) Mouse Recombinant Protein
Product Specifications
Background
Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AA545191; Ddit1; GADD45
Gene ID
13197
UniProt
P48316, Q3UMH6
Accession Number mRNA
NM_007836
Chromosomal Location
6 C1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
18.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gadd45a
Species
Mouse
Protein ID
NP_031862
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/13197
Uniprot URL
https://www.uniprot.org/uniprot/P48316
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007836
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031862
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