Ccdc115 (NM_027159) Mouse Recombinant Protein
Product Specifications
Background
Accessory component of the proton-transporting vacuolar (V) -ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe (2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (By similarity) . May be involved in Golgi homeostasis (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
2310061I09Rik; Ccp1
Gene ID
69668
UniProt
Q8VE99
Accession Number mRNA
NM_027159
Chromosomal Location
1 B
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
19.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ccdc115
Species
Mouse
Protein ID
NP_081435
Overview
Purified recombinant protein of Mouse coiled-coil domain containing 115 (Ccdc115), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/69668
Uniprot URL
https://www.uniprot.org/uniprot/Q8VE99
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_027159
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_081435
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