Dnajb6 (NM_001127367) Mouse Recombinant Protein
Product Specifications
Background
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (By similarity) . Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
HSJ-2; mDj4; Mrj
Gene ID
23950
UniProt
O54946
Accession Number mRNA
NM_001127367
Chromosomal Location
5 B1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
27 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dnajb6
Species
Mouse
Protein ID
NP_001120839
Overview
Purified recombinant protein of Mouse DnaJ heat shock protein family (Hsp40) member B6 (Dnajb6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23950
Uniprot URL
https://www.uniprot.org/uniprot/O54946
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001127367
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001120839
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